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YAP-TEAD-IN-3(IAG933)

Product ID: TAC04304

Cas No. : 2714434-21-4

Purity: 98%+

Product Unit Size	Stock	Prize
10mg	In stock	＄600.00
25mg	In stock	inquiry
50mg	In stock	inquiry
100mg	In stock	inquiry
Bulk Size	Bulk Discount

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COA HNMR HPLC

Description Product Info Shipping and Storage References

Description

YAP-TEAD-IN-3 (compound 155) is a YAP/TAZ-TEAD inhibitor.

YAP-TEAD-IN-3 inhibits Avi-humanTEAD^4217-434 with an IC₅₀ value of 9 nM.

YAP-TEAD-IN-3 also inhibits NCI-H2052 with an GI50 of 0.048 μM (cell proliferation)，and an IC₅₀ of 0.048 μM (YAP reporter gene expression)，respsectively^[1].

Product Info

Cas No.	2714434-21-4
Chemical Name	O=C(NC)C1=CN=C(OCCO)C(F)=C1C2=C3C[C@@]([C@H]4NCCC4)(C5=CC=CC=C5)OC3=CC(F)=C2Cl
Solubility	DMSO : 125 mg/mL (279.06 mM; ultrasonic and warming and heat to 60°C)
Appearance	Solid powder.Please contact us for more accurate information.

Shipping and Storage

Store Temp	Room temperature in continental US; may vary elsewhere.
Ship Temp	Powder：3 years -20°C。In solvent：1 years -80°C

References

1. Tobias Schmelzle, et al. Cancer Res (2023) 83 (8_Supplement): LB319.

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