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Werner syndrome RecQ helicase-IN-3

Product ID: TAC04400

Cas No. : 2869954-98-1

Purity: 98%+

Product Unit Size	Stock	Prize
10mg	In stock	＄498.00
25mg	In stock	inquiry
50mg	In stock	inquiry
100mg	In stock	inquiry
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Description Product Info Shipping and Storage References

Description

Werner syndrome RecQ helicase-IN-3 is a potent and orally active werner syndrome recQ helicase (WRN) inhibitor with an IC₅₀ value of 0.06 µM. Werner syndrome RecQ helicase-IN-3 shows antiproliferative activity. Werner syndrome RecQ helicase-IN-3 shows anticancer activity^[1].

Product Info

Cas No.	2869954-98-1
Formula	C₃₁H₃₀ClF₃N₈O₅
Formula Wt.	687.07
Synonym	[1,2,4]Triazolo[1,5-a]pyrimidine-4(7H)-acetamide, N-[2-chloro-4-(trifluoromethyl)phenyl]-2-(3,6-dihydro-2H-pyran-4-yl)-5-ethyl-6-[4-[(3-hydroxy-2-pyridinyl)carbonyl]-1-piperazinyl]-7-oxo-;Werner syndrome RecQ helicase-IN-3
Solubility	DMSO : 125 mg/mL (279.06 mM; ultrasonic and warming and heat to 60°C)
Appearance	Solid powder.Please contact us for more accurate information.

Shipping and Storage

Store Temp	Room temperature in continental US; may vary elsewhere.
Ship Temp	Powder：3 years -20°C。In solvent：1 years -80°C

References

[1]. Vincent Bordas, et al. Triazolo-pyrimidine analogues for treating diseases connected to the inhibiton of werner syndrome recq helicase (wrn). WO2022249060A1.

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